![]() ![]() However, it is important to note that different forms of chromium are metabolized differently, and thus have different effects on human health ( 9, 19).Ĭases of toxicity with chromium found in supplements are most commonly caused by exceeding the recommended daily doses by 3-18 times ( 13, 14).Įven so, lab studies have shown that even at several thousand times the upper limit of consumption, supplementation with trivalent Cr is considered safe and adequate ( 15). Studies show that chromium picolinate is safe to consume at recommended doses, and is, indeed, necessary for human health ( 1, 11, 12).Ĭhromium has been scrutinized after studies demonstrated that certain forms of the mineral have toxic effects on humans. ![]() In short, trivalent forms of chromium may improve the use of glucose in the blood for energy while it also helps prevent the body from breaking down proteins, like the ones found in your muscles, for energy. While it enhances insulin signaling, chromium picolinate may also inhibit the breakdown of proteins ( 8). Many biochemicals models have set out to propose the mechanism of action of chromium in the body.Ĭhromium is found in such low quantities in the blood, is often studied while individuals are on other medications, and may change its effect based on individual genetics, that studies show that it is difficult to pinpoint exactly how it works ( 4, 5).ĭespite difficulties in understanding how it works in the body, regarding its role in carbohydrate and lipid metabolism, recent studies show that chromodulin, a peptide (protein building block) can saturate itself with chromium and bind to insulin receptors and amplify insulin signaling ( 6).Ī series of other biochemical reactions occur, eventually signaling an increase of glucose uptake and storage ( 7). Normal brain function and other processes in the body.Aids in insulin action and the breakdown of glucose.the breakdown of fats and carbohydrates. ![]()
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